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The "Laboratory Reactions" edition describes organic reactions that occur under strong reaction conditions, offering fundamental concepts of organic chemistry. It serves as an essential guide for students and professionals in organic chemistry, providing a comprehensive overview of both fundamental and advanced organic reactions. Designed to facilitate learning and practical application, this book bridges the gap between theoretical concepts and real-world practice.
In "Laboratory Reactions," readers will find a well-structured and detailed exploration of organic reactions, starting with basic principles and progressing to more complex topics. Each chapter is carefully written to make complex concepts easy to understand with the help of illustrative examples, often with YouTube clips, and useful chemoinformatics applications with Python codes.
I opened a blog called ¡°Jeongbin¡¯s Study Room¡± to collect knowledge from many people. The enthusiasm for organic chemistry is still strong today, but a few years ago, it was significant, as organic chemistry was essential for various exams. Since studying organic chemistry in elementary, middle, and high school was rare, I anticipated a significant academic demand for organic chemistry. Therefore, since 2018, I have been sharing articles on organic chemistry on ¡°Jeongbin¡¯s Study Room¡± and communicating, correcting, and discussing with people. I have had many discussions online with medical professionals, pharmacists, lawyers, current teachers, and professors, among others. Now, as we welcome the new year 2024, I declare that the compilation of organic chemistry knowledge through collective intelligence is complete and I am publishing this book. I hope that this book can lower the barrier of organic chemistry as a field of study.
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Getting Started
Ch. 1: Organic Reaction Overview
Ch. 1: Organic Reaction Overview
1. Overview
2. Types of Organic Reactions
3. Reaction Thermodynamics and Reaction Kinetics
4. Reaction Mechanism
5. Energy Diagram
Ch. 2: Organic Reaction Commons
Ch. 2: Organic Reaction Commons
1. Names of Carbon
2. Acid and Base
3. Nucleophiles:
4. Leaving Groups
5. Solvents
6. EDG, EWG
Ch. 3: Alkyl Halides
Ch. 3: Alkyl Halides
1. Overview
2. Nucleophilic Substitution Reactions
3. SN2 Reaction
4. SN1 Reaction
5. E2 Reaction
6. E1 Reaction
7. E1cB Reaction
8. Bredt's Rule
9. SN2 Reaction vs SN1 Reaction
10. Comparison of SN2, E2, SN1/E1 Reactions
11. Carbon-Carbon Coupling Reactions
12. Synthesis Methods
Ch. 4: Alkenes and Alkynes
Ch. 4: Alkenes and Alkynes
1. Overview
2. Nomenclature of Linear Alkenes and Alkynes
3. Nomenclature of Cyclic Alkenes and Alkynes
4. Electrophilic Reactions of Alkenes
5. Electrophilic Reactions of Alkynes
6. Synthesis Methods of Alkenes
7. Synthesis Methods of Alkynes
Ch. 5: Radical Reactions
Ch. 5: Radical Reactions
1. Radical
2. Overview of Radical Reactions
3. Radical Substitution Reactions
4. Radical Addition Reactions
5. Radical Elimination Reactions
6. Other Radical Reactions
Ch. 6: Conjugation Chemistry
Ch. 6: Conjugation Chemistry
1. Conjugation
2. 2+2 Cycloaddition Reaction
3. 4+2 Cycloaddition Reaction
4. Other Cycloaddition Reactions
Ch. 7: Aromatic Compounds
Ch. 7: Aromatic Compounds
1. Aromaticity
2. Benzene Derivatives Nomenclature
3. Benzene Properties
4. Reaction 1. Electrophilic Aromatic Substitution
5. Reaction 2. Nucleophilic Aromatic Substitution
6. Reaction 3. Other Reactions
7. Substituent Effects
8. Aromatic Side Chain Effects
9. Synthesis Methods
Ch. 8: Redox and Organometallic
Ch. 8: Redox and Organometallic
1. Oxidation-Reduction Reactions
2. Organometallic Reagents
Ch. 9: Organic Reaction Summary
Ch. 9: Organic Reaction Summary